DNA Immunoprecipitation (DIP) for the Determination of DNA-Binding Specificity
نویسندگان
چکیده
منابع مشابه
DIP-chip: rapid and accurate determination of DNA-binding specificity.
We have developed a new method for determining the DNA-binding specificity of proteins. In DIP-chip (DNA immunoprecipitation with microarray detection), protein.DNA complexes are isolated from an in vitro mixture of purified protein and naked genomic DNA. Whole-genome DNA microarrays are used to identify the protein-bound DNA fragments, and the sequence of the identified fragments is used to de...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Protocols
سال: 2008
ISSN: 1559-6095
DOI: 10.1101/pdb.prot4972